Journal: Arthritis Research & Therapy
Article Title: Natural killer cells control a T-helper 1 response in patients with Behçet's disease
doi: 10.1186/ar3005
Figure Lengend Snippet: IL-12 signaling of natural killer cells in inactive Behçet's disease patients . IL-12-induced signal transducer and activator of transduction 4 (Stat4) phosphorylation in natural killer (NK) cells from inactive Behçet's disease (iBD) patients and healthy controls. (a) NK cells from six iBD patients and five healthy controls were stimulated with IL-12, and were subjected to immunoblotting for the detection of phosphorylated Stat4 (pStat4) and total Stat4. (b) Phosphorylation status of Stat4, which is expressed as the ratio of the intensity of pStat4 to that of total Stat4, in NK cells from six iBD patients and five healthy controls. Horizontal bars, mean values.
Article Snippet: The antibodies used were rabbit anti-phosphorylated-Stat4 polyclonal antibodies (Zymed Laboratories, South San Francisco, CA, USA) and rabbit anti-Stat4 polyclonal antibodies (Santa Cruz Biotechnology, Santa Cruz, CA, USA).
Techniques: Transduction, Western Blot